Publications and Grants

Research Grants and Projects

04/2023 – 03/2026 : Canadian Institutes of Health Research (CIHR) – Accelerating clinical trials (ACT) – Canada.

01/2023 – 05/2024 : Fonds de Recherche du Québec (FRQS) – Development of Automated Learning Strategies to Determine Phenogroups, Progression, and Clinical Outcomes of Aortic Valve Stenosis

10/2022 – 09/2027 : Canadian Institutes of Health Research (CIHR) – Imaging substudy of the BEST trial: Balloon-Expandable versus self-expanding transcatheter heart valve for treatment of symptomatic native aortic valve stenosis.

06/2022- 03/2024 : Pfizer Canada ULC – Prostate and cardiac amyloid incidence awareness in patients with atrial fibrillation.

12/2021 – 11/2028 : Canadian Institutes of Health Research (CIHR) – Canada Research Chair in Valvular Heart Diseases.

09/2021 – 08/2026 : Canadian Institutes of Health Research (CIHR) – Blocking the effects of serotonin to prevent ischemic mitral regurgitation: a randomized trial.

08/2021 – 12/2024 : Centre d’Innovation Cardiovasculaire (CIC) – Standardized invasive hemodynamics for monitoring acute and long-term valve performance in patients with elevated gradients post transcatheter aortic valve replacement: The Discordance TAVR study.

03/2018 – 09/2026: Canadian Institutes of Health Research (CIHR) – Finding the molecular drivers of calcific aortic valve stenosis.

10/2015 – 12/2025 : Cardiovascular Research Foundation (CRF) – Transcatheter aortic valve replacement to UNload the left ventricle in patients with advanced heart failure: a randomized trial (TAVR UNLOAD).

Recent Publications (The Last Twenty)

827 Referenced Publications, Book Chapter 35

Articles published in press :

Cardiac Damage Staging in Aortic Stenosis: Ready for Prime Time. Pibarot P. Journal of the American College of Cardiology (JACC) : Cardiovascular Interventions. 2024 April 22.

Impact of Prosthesis-Patient Mismatch After Surgical Aortic Valve Replacement: Systematic Review and Meta-Analysis of Reconstructed Time-to-Event Data of 122 989 Patients With 592 952 Patient-Years. Sá MP, Jacquemyn X, Van den Eynde J, Chu D, Serna-Gallegos D, Ebels T, Clavel MA, Pibarot P, Sultan I. Journal of the American Heart Association. 2024 April 2.

Reply to Association between prosthesis-patient mismatch and valve thrombosis: an independent link ? Eric Durand, Thomas Levesque, Charles Fauvel , Pibarot P , Hélène Eltchaninoff . Canadian Journal of Cardiology. 2024 March 29.

Computed tomography calcium scoring in aortic stenosis: bicuspid versus tricuspid morphology. Ye Z, Clavel MA, Foley TA, Pibarot P, Enriquez-Sarano M, Michelena HI. Heart. 2024 March 22.

Angiotensin II receptor blockers are associated with reduced valvular fibrosis in females with aortic stenosis. Carter-Storch R, Le Nezet E, Ali M, Powers A, Haujir A, Demers K, Couture C, Dumont É, Trahan S, Pagé S, Dagenais F, Pibarot P, Dahl JS, Clavel MA. Canadian Journal of Cardiology. 2024 March 20.
Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation. Thériault S, Li Z, Abner E, Luan J, Manikpurage HD, Houessou U, Zamani P, Briend M; Estonian Biobank Research Team;
Boudreau DK, Gaudreault N, Frenette L, Argaud D, Dahmene M, Dagenais F, Clavel MA, Pibarot P, Arsenault BJ, Boekholdt SM, Wareham NJ, Esko T, Mathieu P, Bossé Y. Nature Communications. 2024 March 18.
Leaflet Mechanical Stress in Different Designs and Generations of Transcatheter Aortic Valves: An in Vitro Study. Stanová V, Rieu R, Thollon L, Salaun E, Rodés-Cabau J, Côté N, Mantovani D, Pibarot P. Structural Heart. 2023 December 19, review March 2024.
Transcatheter or surgical aortic valve replacement in patients with severe aortic stenosis and small aortic annulus: A randomized clinical trial. Rodés-Cabau J, Ribeiro H, Mohammadi S, Serra V, Al-Atassi T, Iniguez A, Vilalta V, Nombela-Franco L, Saez de Ibarra JI, Auffret V, Forcillo J, Conradi L, Urena M, Moris C, Muñoz-Garcia A, Paradis JM, Dumont E, Kalavrouziotis D, Pomerantzeff PM, Rosa VEE, Lopes MP, Sureda C, Jimenez Diaz VA, Giuliani C, Avvedimento M, Pelletier-Beaumont E, Pibarot P. AHA Journals – Circulation. 2024 February 27.

Long-Term Survival and Quality of Life Following Transcatheter Aortic Valve Replacement in Nonagenarians. Madanat L, Allam M, Khalili H, Rabah A, Tariq R, Zamzam M, Rodés-Cabau J, Pilgrim T, Okuno T, Elmariah S, Pibarot P, Abbas AE. American Journal of Cardiology. 2024 February 15.

Combined Value of Dimensionless Index and Transvalvular Flow Rate in Risk Stratification of Aortic Stenosis. Namasivayam M, Churchill TW, Capoulade R, Pibarot P, Danik JS, Picard MH, Levine RA, Hung J. American Journal of Cardiology. 2024 February 15.

Patient-Prosthesis Mismatch After Surgical Aortic Valve Replacement: Analysis of the PARTNER Trials. Thourani VH, Abbas AE, Ternacle J, Hahn RT, Makkar R, Kodali SK, George I, Kapadia S,nSvensson LG, Szeto WY, Herrmann HC, Ailawadi G, Leipsic J, Blanke P, Webb J, Jaber WA, Russo M, Malaisrie SC, Yadav P, Clavel MA, Khalique OK, Weissman NJ, Douglas P, Bax J, Dahou A, Xu K, Bapat V, Alu MC, Leon MB, Mack MJ, Pibarot P. Annals of Thoracic Surgery. 2024 February 3.
Design and rationale of the evaluation of transcatheter aortic valve replacement compared to surveillance for patients with asymptomatic severe aortic stenosis: The EARLY TAVR trial. Généreux P, Schwartz A, Oldemeyer B, Cohen DJ, Redfors B, Prince H, Zhao Y, Lindman BR, Pibarot P, Leon MB. American Journal of Cardiology.. 2024 February 1.

European Society of Cardiology Quality indicators for the care and outcomes of adults undergoing transcatheter aortic valve implantation. Ali N, Aktaa S, Younsi T, Beska B, Batra G, Blackman DJ, James S, Ludman P, Mamas MA, Abdel-Wahab M, Borregaard B, Iung B, Joner M, Kunadian V, Modine T, Neylon A, Petronio AS, Pibarot P, Popescu BA, Sabaté M, Stortecky S, Teles RC, Treede H, Gale CP. European Heart Journal – Quality of Care and Clinical Outcomes. 2024 January 23.

Diagnostic accuracy of virtual non-contrast CT for aortic valve stenosis severity evaluation. Lorenzatti D, Piña P, Daich J, Scotti A, Perez-Cervera J, Miranda R, Feinberg AJ, Halliburton SS, Ivanc TB, Schenone AL, Kuno T, Latib A, Dey D, Pibarot P, Dweck MR, Garcia MJ, Slipczuk L. Journal of Cardiovascular Computed Tomography, 2024 Jan-Feb.

Diastolic dysfunction and health status outcomes after transcatheter aortic valve replacement. El-Zein RS, Malik AO, Cohen DJ, Spertus JA, Saxon JT, Pibarot P, Hahn RT, Alu MC, Shang K, Kodali SK, Thourani VH, Leon MB, Mack MJ, Chhatriwalla AK.Struct Heart. 2023 September 27.

Discordant Low-Gradient Aortic Stenosis: Assessing the Valve and the Myocardium. Pibarot P. Texas Heart Institute Journal. 2024 January 15.

Impact of prosthesis-patient mismatch after transcatheter aortic valve replacement. Levesque T, Eltchaninoff H, Chabannes R, Barbe T, Dosseh O, Tron C, Bettinger N, Bouhzam N, Hemery T, Le Pessec G, Fauvel C, Cribier A, Pibarot P, Durand E. Canadian
Journal of Cardiology. 2024 January 1.

Long-term outcomes of Ross procedure versus mechanical aortic valve replacement: meta-analysis of reconstructed time-to-event data. Sá MP, Van den Eynde J, Jacquemyn X, Tasoudis P, Erten O, McDonald C, Weymann A, Ruhparwar A, Clavel MA, Pibarot P, Calhoon J, Ramlawi B. Trends in Cardiovascular Medicine. 2022 June 21, review January 2024.
Balloon-vs. self-expanding transcatheter valve for failed small surgical aortic bioprostheses : 1-year results of the LYTEN trial. Nuche J, Abbas AE, Serra V, Vilalta V, Nombela-Franco L, Regueiro A, Al-Azizi KM, Iskander A, Conradi L, Forcillo J, Lilly S, Calabuig A, Fernandez-Nofrerias E, Mohammadi S, Giuliani C, Pelletier-Beaumont E, Pibarot P, Rodés-Cabau J. JACC: Cardiovascular Interventions. 2023 December 25.
Impact of arteriovenous fistula on flow states in the evaluation of aortic stenosis among ESKD patients on dialysis. Ogugua FM, Mathew RO, Ternacle J, Rodin H, Pibarot P, Shroff GR. Echocardiography. 2023 December 19.